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The Least Common Multiple of two or more algebraic expressions is the expression of the lowest degree (or power), divisible by each of them without remainder.
The LCM of a number or an algebraic expression by factorization method can be determined using the following steps:

(i) Each expression must be resolved into its simple factors.

(ii) The highest power of the common factors will be the LCM.

(iii) If the expressions have numerical coefficients, find their LCM.

(iv) The product of the LCM of factors and coefficient is the required LCM.
Example:
1. Find the LCM of 16x^3y^2z, 45xy^9z^7,12x^9y^2z
 
Solution:
 
Step 1: Let us find the LCM of the numerical coefficients.
 
16 = 2^4, 45 = 3 \times 3 \times 5, 12 = 2 \times 2 \times 3
 
LCM(16, 45, 12) = 2^4 \times 3 \times 3 \times 5 = 720
 
Step 2: Let us find the LCM of the variable terms.
 
LCM(x^3y^2z, xy^9z^7, x^9y^2z) = x^9y^9z^7
 
Step 3: The product of the LCM of the numerical coefficients and variable terms is the required LCM.
 
LCM(16x^3y^2z, 45xy^9z^7,12x^9y^2z) = 720x^9y^9z^7
 
Thus, the required LCM is 720x^9y^9z^7.
 
 
2. Find the LCM of 21(x^4 - x^2), 16(x^2 + 3x)^2.
 
Solution:
 
21(x^4 - x^2) = 3 \times 7 \times x^2 \times (x^2 - 1)
 
16(x^2 + 3x)^2 = 2^4 \times (x^4 + 6x^3 + 9x^2) = 2^4 \times x^2 \times (x^2 + 6x + 9) = 2^4 \times x^2 \times (x + 3)(x + 3)
 
The LCM of 21(x^4 - x^2), 16(x^2 + 3x)^2 is given by:
 
LCM = 3 \times 7 \times 2^4 \times x^2 \times (x + 1)(x - 1) \times (x + 3)(x + 3)
 
= 336 \times x^2(x^2 -1)(x + 3)^2
 
Therefore, LCM(21(x^4 - x^2), 16(x^2 + 3x)^2) = 336 \times x^2(x^2 -1)(x + 3)^2.